The price of an ordinary polystyrene culture dish on the market is only one CNY, and Qingdao Jindian Biochemical Equipment Co., Ltd. sells more than 55 yuan using the culture technology. The unremarkable product has made high-tech and high added value. The secret of the Golden Code lies in continuous innovation and upgrading.
Founded in 1992, Jindian is dedicated to the research, development, manufacture and sales of disposable medical products in hospitals and laboratories. It is the first production plant in China with a complete series of culture dishes, and is the only manufacturer of culture dishes in China that has mastered coating technology. After more than 20 years of development, Jindian’s petri dish products have been developed using self-developed chemical gas deposition plasma and polymer wet coating technology, and have developed advanced-grade adherent cell culture dishes and low-cell-attached suspension culture dishes. Leading the country and moving towards the international advanced level.
Petri dish capable of culturing cells
At present, the development of life sciences is changing with each passing day, and the strategic position of biotechnology in leading future economic and social development is increasingly prominent. Research on biotechnology, from viruses, bacteria, plants, animals to human genetic research, can not be separated from large and small vehicles.
So, don’t underestimate these bottles and cans. “In the past, cell activity and structure were observed under a microscope for up to four days. Now we have a suspension cell culture dish that can grow cells for a long time to grow and grow for twenty-six or six days. There is no problem. Collagen culture dishes can make some cells that are not easy to grow grow in it, which is a leap.” Jin Qing, general manager of Jindian Company said.
In medical experiments, the effect of drugs on cancer cells is studied. The smaller the dose, the better the effect. The common culture dishes are mostly adherent growth culture dishes. It is this problem that is solved by the Golden Code. The culture dish is made into two categories: adherent and suspended. The cell suspension culture time is longer by the coating technology. The culture dish for suspending cells can make the cells all-roundly affected by the drug, and more accurately reflect the influence of the amount of the drug on the cells. This product is currently not produced by other manufacturers in China, and is comparable to the products of the global giant Corning.
More than that, the Golden Code continues to overcome industry problems and seize the commanding heights. At present, the first generation of cell culture, liver and kidney cell culture, endothelial cell and neovascular cell culture, nerve cell culture, and stem cell differentiation culture require the use of collagen layer-linked protein, polylysine and other coated culture dishes. In addition to mastering this wet coating technology, Jindian also jumped out of the traditional framework, using chemical gas deposition plasma technology to coat collagen-like materials to the surface of the culture dish, which is a progressive product compared to collagen culture dishes. Its function is similar to that of collagen culture dish, but the material used is not derived from animals. Its performance is better than traditional culture dish. It has good repeatability and good stability, long service life and can be stored at room temperature. The technology has reached the international leading level.
Starting from a simple and unskilled petri dish, mastering the techniques of adherence and suspension coating, to the first collagen-like coating, to the development of intelligent culture dishes, Jindian has been sticking to this segment, and has only been carried out since 2016. More than 10 scientific research projects, innovation is the driving force for its continuous upgrading.
Yan Qing introduced: “The main culture of the culture dish accounts for 70% of all our business. After mastering the coating technology, all the centrifuge tubes and the like can be coated, which can better meet the needs of scientific research institutions and hospitals. With the development of technology, new process requirements will continue to emerge in the future, and we can keep up.”
Building a cell culture factory
For a long time, the low-end petri dish market has experienced fierce competition due to low technical content. The development of Jindian to the high-end petri dish market has undergone a five-year transformation.
Based on the forward-looking smart petri dish technology, Bengqing has a bigger idea. He is not satisfied with only one product, but wants to open up the entire industrial chain, and the whole cell culture into an industry, combined with the hospital surgery center for the regeneration and repair of damaged tissue. This is actually the concept of regenerative medicine.
Yan Qing is expected to have a big move within two years. Currently, he is improving the technology in terms of cost and data stability. The registered patents and related approvals are rolled out and extended to the hospital. The most important application for the market is the regeneration of damaged corneal epithelium.
There are 4 million corneal blind patients in China, and the number of cases is more than 100,000 per year, and the number of corneal transplants per year is only about 5,000. The human donor’s cornea is seriously deficient, and the bioengineered cornea may have rejection. As a result, many patients with corneal blindness cannot be treated in time. If the cornea can be cultured from the patient’s own cells, this will be a potentially huge market.
Jindian’s eyes are not only domestic, but also a broader foreign market. It is expected to become a platform for medical service integration, to accommodate overseas users through convenient transportation conditions, open to local patients and scientific research institutions, and to realize the transformation and application of clinical research results.
“I am going to apply for four or five hundred mu of land. I will make a small attempt first, and I will not invest too much, and then continue to expand. The first phase of the cell culture factory must have, then the R&D building and the access exchange center. We are responsible for training Cell and team guidance, transplantation by the hospital. Stem cell repair and regeneration research must also require the corresponding vehicle, that is the future direction.” Yan Qing said.
“Abandoning the interests and standing at a higher height, we are solving the problem of revisiting the light for mankind. This is not out of reach, and will become a reality in the near future.” Here, the excitement of Yan Qing is beyond words.
Regenerative medicine has a wide range of application prospects in terms of cardiovascular diseases, autoimmune diseases, and diabetes, which are difficult to achieve with traditional treatment methods. Entering the clinical application and industrialization of regenerative medicine, this will be an uneven and promising road. Jindian relies on basic research to lay out the industrialization chain in advance, and looks forward to having a place in this huge market in the future. (Qingdao Daily / Qingdao View / Qing Daily reporter Zhou Xiaofeng)
Post time: Nov-22-2017